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In cases where medications are determined to be unsafe, the researchers suggested that exercise therapy may be used to successfully treat erectile dysfunction.
Ejaculation, the release of semen at climax, is triggered when the man reaches a critical level of excitement. Sexual stimulation causes nerves in the penis to send chemical messages or impulses to the spinal cord and into the brain. There, more chemical messages are sent back to the penis causing ejaculation.
At least 7 PDE classes are known, many with subtypes identified by structure and function. PDE-5 is cGMP-specific and is a major cGMP-hydrolyzing enzyme in the vascular smooth muscle of the penis. The newer agents, vardenafil and tadalafil, are more specific and potent cGMP inhibitors than sildenafil. Both of the newest agents are PDE-5 inhibitors, which are significantly more selective in their inhibition.
Its causes remain a mystery, Vorona said, but some evidence suggests it's related to reduced levels of iron and the neurotransmitter known as dopamine in the brain. Those who have the neurological disorder complain of an almost irresistible urge to move their legs.
Currently in phase II development, Zoraxel is based on clavulanic acid and allegedly alters brain dopamine and serotonine levels, thus improving erectile function.
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See Also: Health & Medicine Men's Health Erectile Dysfunction Sexual Health Mind & Brain Sleep Disorders Gender Difference Insomnia Reference Restless legs syndrome Sexual dysfunction Dorian Gray syndrome Erectile dysfunction
For any medication to be effective, the physiologic components involved in the erectile process must be functional. Serious impairments render the medication either completely or partially ineffective.
Treatment depends on the cause. Testosterone supplements may be used for cases due to hormonal deficiency. However, the cause is more usually lack of adequate penile blood supply as a result of damage to inner walls of blood vessels. This damage is more frequent in older men, and often associated with disease, in particular diabetes.
Peyronie's disease is a rare inflammatory condition that causes scarring of erectile tissue. Scarring produces curvature of the penis that can interfere with sexual function and cause painful erections.
NMDA-induced erections were significantly blunted in diabetic rats compared with control rats
The following health professionals can evaluate symptoms of erection problems:
7 Common Health Problems that Affect Men's Sexual Health
To understand the link between alcohol and erectile dysfunction, the process of achieving an erection needs to be understood.
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SUNDAY, Dec. 30 (HealthDay News) -- If heart disease, stroke and certain cancers haven't been reason enough for men to quit smoking, consider this: The habit also increases the risk of erectile dysfunction.