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Early last week, someone added an old post from this blog to StumbleUpon. It garnered about 200 pageviews that day, making a little spike in my site traffic report. The post was from December 2006, and I didn’t even remember writing it. Everyday journalism, on the job I wrote about how a reporter would do [...]
In the midst of layoffs and announcements of newsroom downsizing, I continue to receive good reports from former students who are working in online journalism. They’re not always doing the work they could be doing (and should be encouraged to produce), but they’re not scared of losing their job tomorrow, either. This one comes from [...]
A nice use of blogging for journalism interns, shared by Penny Bender Fuchs, at the University of Maryland j-school: I have my 62 summer interns blogging rather than writing papers on their experiences. They are required to post to the blog at least seven times during the summer, answering specific questions (such as: Describe your [...]
“The New York Times is doing all this video for the Business section. If you never look at their Business section online, you’ll never find it.” My friend Ehrin and I were somewhere in Hanoi, eating pho cuon at a table on the sidewalk, when he told me this. He said the Times has been [...]
Some people at a U.S. embassy reception tonight, here in Hanoi, expressed excitement on hearing that I am teaching online journalism to about 30 Vietnamese journalists. An American suggested that I should teach them how to stay safe and not get thrown into jail. I ventured that they probably think enough about that, without any [...]
The Associated Press is touting something they call “1-2-3 filing.” It reminds me of Bloomberg’s model (developed, what, 20 years ago?) and more recently, the BBC News online method. But derivative or not, it makes darned good sense. AP Executive Editor Kathleen Carroll explained the new model at the World Association of Newspapers conference on [...]
From Beet.tv: The reporters in the print newsroom are integrating video shooting into their normal, everyday storytelling, Chet says.
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The resulting relaxation of the smooth muscle of the penile arterial walls created an unexpected two-hour erection. This mistake prompted serious research into the use of injectable medications to relieve ED. Around the same time, Giles Brindley, a British physiologist and research scientist, discovered that injecting the drug phenoxybenzamine into the corpora cavernosa of the penis could produce an erection within minutes. At a meeting in Paris in 1984, New York urologist Dr. Adrian Zorgniotti presented his first case studies of self-injection utilizing a combination of papaverine and phentolamine. The latter drug blocks the action of neurotransmitters that cause vasoconstriction, causing the smooth muscles of the penis to relax. Two years later, Japanese researchers presented evidence that injecting the drug prostaglandin E-1 produced powerful erections. 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Vardenafil has distinguished itself by demonstrating efficacy in patients who have previously undergone radical prostatectomy for localized prostate cancer (a group that had been difficult to treat because of nerve and vascular injury secondary to surgery) and in patients with diabetes.34,35 Common adverse effects include headache, flushing, rhinitis, dyspepsia, or indigestion; assess cardiovascular status before use; caution with left ventricular outflow obstruction or conditions aggravated by hypotension; caution with hepatic or renal impairment (decrease dose); may cause prolonged or painful erection; may cause back pain or myalgias Concurrent administration with potent CYP3A4 inhibitors (eg, ketoconazole, ritonavir): Not to exceed 10 mg PO q72h prn; no difference in safety or efficacy has been demonstrated in men >65 y compared with younger men "The concept that a venom can have an effect on erection is highly plausible," said Dr. Arnold Melman, chief of urology at Montefiore Medical Center in New York City. 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Uprima works by stimulating the brain chemical dopamine, which heightens sexual interest and sensations. A small number of people passed out after taking Uprima, so its release in the U.S. is on hold; however, it is currently available in Europe. Clinical trials are also currently being conducted on a nasal spray form of this drug. If the Seat Fits PDE5 blockade not only increases intratumoral CD8+ infiltration and activation but also enhances their tumoricidal activity (Fig. 2). The ability to favorably alter the intratumoral microenvironment, thereby permitting tumor-specific T cells to directly interact with their targets, is critical for maximal antitumor immunity. Effective immunotherapy requires tumor-specific CTLs to infiltrate the tumor and kill their target in situ. Although no clinical advantage was derived by the presence of tumor-specific CTLs in the peripheral blood in melanoma patients (40), their frequency in the tumor correlated with a favorable prognosis (41). These clinical observations seem to be confirmed in our model where sildenafil treatment (a) increased the CD8+ T cell tumor infiltration (Fig. 4 B) and (b) increased the percentage of activated T cells (Fig. 4, C and D). Moreover, the number of tumor-infiltrating T cells directly correlated with a measurable antitumor effect (Fig. 3).